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Production of erythrocyte autoantibodies in NZB mice is inhibited by CD4 antibodies.

NZB mice spontaneously develop haemolytic anaemia as the result of production of erythrocyte autoantibodies. The mechanisms leading to breakdown in tolerance to erythrocyte autoantigens are unknown. Antibodies to CD4 have been successfully used to treat several murine models of autoimmune disease. I...

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Autors principals: Oliveira, G G, Hutchings, P R, Roitt, I M, Lydyard, P M
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534883/
https://ncbi.nlm.nih.gov/pubmed/8187337
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