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Antibody affinity maturation: the role of CD8+ cells.
The cellular control of antibody affinity maturation has been studied in mice genetically selected for their failure to demonstrate an increase in affinity following immunization (low-affinity N/M mice). Depletion of CD8+ cells in low N/M mice by thymectomy and/or anti-CD8 antibody treatment resulte...
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Auteurs principaux: | , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
1989
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1534833/ https://ncbi.nlm.nih.gov/pubmed/2532994 |
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