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Low antibody affinity restricted to the IgA isotype in IgA nephropathy.

Antibody affinity affects the handling and behaviour of immune complexes, and experimental studies have shown that animals which produce predominantly low-affinity antibody are prone to immune complex deposition resulting in glomerulonephritis. In order to investigate the potential role of antibody...

詳細記述

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書誌詳細
主要な著者: Layward, L, Allen, A C, Hattersley, J M, Harper, S J, Feehally, J
フォーマット: Artigo
言語:Inglês
出版事項: 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534647/
https://ncbi.nlm.nih.gov/pubmed/8287607
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