Low antibody affinity restricted to the IgA isotype in IgA nephropathy.

Antibody affinity affects the handling and behaviour of immune complexes, and experimental studies have shown that animals which produce predominantly low-affinity antibody are prone to immune complex deposition resulting in glomerulonephritis. In order to investigate the potential role of antibody...

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Bibliografiska uppgifter
Huvudupphovsmän: Layward, L, Allen, A C, Hattersley, J M, Harper, S J, Feehally, J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534647/
https://ncbi.nlm.nih.gov/pubmed/8287607
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