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Low antibody affinity restricted to the IgA isotype in IgA nephropathy.

Antibody affinity affects the handling and behaviour of immune complexes, and experimental studies have shown that animals which produce predominantly low-affinity antibody are prone to immune complex deposition resulting in glomerulonephritis. In order to investigate the potential role of antibody...

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Detalhes bibliográficos
Main Authors: Layward, L, Allen, A C, Hattersley, J M, Harper, S J, Feehally, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534647/
https://ncbi.nlm.nih.gov/pubmed/8287607
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