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The rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers

BACKGROUND: The rhomboid family of polytopic membrane proteins shows a level of evolutionary conservation unique among membrane proteins. They are present in nearly all the sequenced genomes of archaea, bacteria and eukaryotes, with the exception of several species with small genomes. On the basis o...

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Bibliographic Details
Main Authors: Koonin, Eugene V, Makarova, Kira S, Rogozin, Igor B, Davidovic, Laetitia, Letellier, Marie-Claude, Pellegrini, Luca
Format: Artigo
Language:Inglês
Published: BioMed Central 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC153459/
https://ncbi.nlm.nih.gov/pubmed/12620104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2003-4-3-r19
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