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B7/BB1 provides an important costimulatory signal for CD3-mediated T lymphocyte proliferation in patients with systemic lupus erythematosus (SLE).

Successful T cell activation via the T cell receptor (TCR)/CD3 complex requires at least one contact-dependent second signal delivered by costimulatory molecules, including the B7/BB1 molecule, that are present on antigen-presenting cells (APC). SLE is characterized by multiple complex lymphocyte ab...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sfikakis, P P, Oglesby, R, Sfikakis, P, Tsokos, G C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534533/
https://ncbi.nlm.nih.gov/pubmed/7512010
Etiketak: Etiketa erantsi
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