Dichotomy of the T cell response to Leishmania antigens in patients suffering from cutaneous leishmaniasis; absence or scarcity of Th1 activity is associated with severe infections.

The T cell response was studied in 25 patients suffering from cutaneous leishmaniasis caused by Leishmania major with severe (n = 10) and mild (n = 15) disease manifestations. Peripheral blood mononuclear cells (PBMC) from the patients were activated by sonicates of Leishmania promastigotes (LMP) an...

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Detalhes bibliográficos
Main Authors: Gaafar, A, Kharazmi, A, Ismail, A, Kemp, M, Hey, A, Christensen, C B, Dafalla, M, el Kadaro, A Y, el Hassan, A M, Theander, T G
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534327/
https://ncbi.nlm.nih.gov/pubmed/7743662
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