Tumour necrosis factor-alpha (TNF-alpha) synthesis is associated with the skin and peripheral nerve pathology of leprosy reversal reactions.

Leprosy may be complicated by episodes of increased cell-mediated immunity towards Mycobacterium leprae (reversal reactions) which result in severe local immunopathology in skin lesions and peripheral nerves. Using in situ hybridization and MoAb techniques we have demonstrated TNF-alpha mRNA and TNF...

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Detalhes bibliográficos
Main Authors: Khanolkar-Young, S, Rayment, N, Brickell, P M, Katz, D R, Vinayakumar, S, Colston, M J, Lockwood, D N
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534301/
https://ncbi.nlm.nih.gov/pubmed/7851011
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