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Insulin-like growth factor-1 (IGF-1) induces the activation/phosphorylation of Akt kinase and cAMP response element-binding protein (CREB) by activating different signaling pathways in PC12 cells

BACKGROUND: Insulin-like growth factor-1 (IGF-1) is a polypeptide growth factor with a variety of functions in both neuronal and non-neuronal cells. IGF-1 plays anti-apoptotic and other functions by activating multiple signaling pathways including Akt kinase, a serine/threonine kinase essential for...

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Detalhes bibliográficos
Main Authors: Zheng, Wen-Hua, Quirion, Rémi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534052/
https://ncbi.nlm.nih.gov/pubmed/16792806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-7-51
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