Enzyme-Linked Immunosorbent Assay Specific to Dengue Virus Type 1 Nonstructural Protein NS1 Reveals Circulation of the Antigen in the Blood during the Acute Phase of Disease in Patients Experiencing Primary or Secondary Infections

During flavivirus infection in vitro, nonstructural protein NS1 is released in a host-restricted fashion from infected mammalian cells but not vector-derived insect cells. In order to analyze the biological relevance of NS1 secretion in vivo, we developed a sensitive enzyme-linked immunosorbent assa...

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Main Authors: Alcon, Sophie, Talarmin, Antoine, Debruyne, Monique, Falconar, Andrew, Deubel, Vincent, Flamand, Marie
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Virology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC153354/
https://ncbi.nlm.nih.gov/pubmed/11825945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.40.2.376-381.2002
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