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Aminoglycoside Resistance Resulting from Tight Drug Binding to an Altered Aminoglycoside Acetyltransferase

The aacA29b gene, which confers an atypical aminoglycoside resistance pattern to Escherichia coli, was identified on a class 1 integron from a multidrug-resistant isolate of Pseudomonas aeruginosa. On the basis of amino acid sequence homology, it was proposed that the gene encoded a 6′-N-acetyltrans...

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Bibliografiske detaljer
Main Authors: Magnet, Sophie, Smith, Terry-Ann, Zheng, Renjian, Nordmann, Patrice, Blanchard, John S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC153337/
https://ncbi.nlm.nih.gov/pubmed/12709325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1577-1583.2003
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