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A physiologically based pharmacokinetic model for 2,4-toluenediamine leached from polyurethane foam-covered breast implants.

Physiologically based pharmacokinetic (PBPK) modeling was used to assess the low-dose exposure of patients to the carcinogen 2, 4-toluenediamine (2,4-TDA) released from the degradation of the polyester urethane foam (PU) used in Meme silicone breast implants. The tissues are represented as five comp...

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Autors principals: Luu, H M, Hutter, J C, Bushar, H F
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1533137/
https://ncbi.nlm.nih.gov/pubmed/9637796
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