Use of High-Performance Liquid Chromatography To Study the Pharmacokinetics of Colistin Sulfate in Rats following Intravenous Administration

The pharmacokinetics of colistin was investigated using specific high-performance liquid chromatography (HPLC) to measure the concentrations of colistin and colistin A and B in plasma and urine in five rats after administration of an intravenous bolus of 1 mg of colistin sulfate/kg of body weight. T...

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Main Authors: Li, Jian, Milne, Robert W., Nation, Roger L., Turnidge, John D., Smeaton, Timothy C., Coulthard, Kingsley
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC153303/
https://ncbi.nlm.nih.gov/pubmed/12709357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1766-1770.2003
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