Humoral Immunity Reflects Altered T Helper Cell Bias in Borrelia burgdorferi-Infected γδ T-Cell-Deficient Mice

In murine Lyme borreliosis, the absence of γδ T lymphocytes augments the T helper cell 2 type humoral response but does not alter disease susceptibility. Arthropod transmission of Borrelia burgdorferi spirochetes results in similar antibody isotypes when γδ T cells are present, suggesting that vecto...

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Bibliographic Details
Main Authors: Bockenstedt, Linda K., Shanafelt, Marie-Claude, Belperron, Alexia, Mao, Jialing, Barthold, Stephen W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Bacterial Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC153287/
https://ncbi.nlm.nih.gov/pubmed/12704174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.5.2938-2940.2003
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