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Modulation of Myosin Light-Chain Phosphorylation by p21-Activated Kinase 1 in Escherichia coli Invasion of Human Brain Microvascular Endothelial Cells

Cytoskeletal dynamics, modulated by actin-myosin interactions, play an important role in Escherichia coli K1 invasion of human brain microvascular endothelial cells (HBMEC). Herein, we show that inhibitors of myosin function, butanedione monoxide and ML-7, significantly blocked the E. coli invasion...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Rudrabhatla, Rajyalakshmi S., Sukumaran, Sunil K., Bokoch, Gary M., Prasadarao, Nemani V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12704153/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.5.2787-2797.2003
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