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Global Effects of Virulence Gene Regulators in a Bacillus anthracis Strain with Both Virulence Plasmids

Control of anthrax toxin and capsule synthesis, the two major virulence factors of Bacillus anthracis, has been associated with two regulatory genes, atxA and acpA, located on virulence plasmids pXO1 and pXO2, respectively. We used transcriptional profiling to determine whether atxA and/or acpA cont...

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Autori principali: Bourgogne, Agathe, Drysdale, Melissa, Hilsenbeck, Susan G., Peterson, Scott N., Koehler, Theresa M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC153248/
https://ncbi.nlm.nih.gov/pubmed/12704148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.5.2736-2743.2003
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