Rapid Apoptosis Induced by Shiga Toxin in HeLa Cells

Apoptosis was induced rapidly in HeLa cells after exposure to bacterial Shiga toxin (Stx1 and Stx2; 10 ng/ml). Approximately 60% of HeLa cells became apoptotic within 4 h as detected by DNA fragmentation, terminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) assay, and...

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Auteurs principaux: Fujii, Jun, Matsui, Takashi, Heatherly, Daniel P., Schlegel, Kailo H., Lobo, Peter I., Yutsudo, Takashi, Ciraolo, Georgianne M., Morris, Randal E., Obrig, Tom
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
Sujets:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC153243/
https://ncbi.nlm.nih.gov/pubmed/12704147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.5.2724-2735.2003
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