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α-Helix nucleation by a calcium-binding peptide loop
A 12-residue peptide AcDKDGDGYISAAENH(2) analogous to the third calcium-binding loop of calmodulin strongly coordinates lanthanide ions (K = 10(5) M(−1)). When metal saturated, the peptide adopts a very rigid structure, the same as in the native protein, with three last residues AAE fixed in the α-h...
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| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15323/ https://ncbi.nlm.nih.gov/pubmed/9927666 |
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