Increased Expression of TATA-Binding Protein, the Central Transcription Factor, Can Contribute to Oncogenesis

Despite the central role of TATA-binding protein (TBP) in transcription, changes in cellular TBP concentration produce selective effects on gene expression. Moreover, TBP is up-regulated by oncogenic signaling pathways. These findings suggest that TBP could be a nexus in pathways that regulate cell...

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Autori principali: Johnson, Sandra A. S., Dubeau, Louis, Kawalek, Michael, Dervan, Andrew, Schönthal, Axel H., Dang, Chi V., Johnson, Deborah L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Transcriptional Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC153209/
https://ncbi.nlm.nih.gov/pubmed/12697807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.9.3043-3051.2003
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