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Regulation of E2F1 by BRCT Domain-Containing Protein TopBP1

The E2F transcription factor integrates cellular signals and coordinates cell cycle progression. Our prior studies demonstrated selective induction and stabilization of E2F1 through ATM-dependent phosphorylation in response to DNA damage. Here we report that DNA topoisomerase IIβ binding protein 1 (...

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Udgivet i:Mol Cell Biol
Principais autores: Liu, Kang, Lin, Fang-Tsyr, Ruppert, J. Michael, Lin, Weei-Chin
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153207/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12697828/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.9.3287-3304.2003
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