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Death Inducer-Obliterator 1 Triggers Apoptosis after Nuclear Translocation and Caspase Upregulation

Death inducer-obliterator 1 (DIO-1) is a gene that is upregulated early in apoptosis. Here we report that in healthy cells, the DIO-1 gene product was located in the cytoplasm, where it formed oligomers. After interleukin-3 starvation or c-Myc-induced apoptosis in serum-free conditions, DIO-1 transl...

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Main Authors: García-Domingo, David, Ramírez, Dorian, González de Buitrago, Gonzalo, Martínez-A, Carlos
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC153187/
https://ncbi.nlm.nih.gov/pubmed/12697821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.9.3216-3225.2003
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