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STAT6 Mediates Interleukin-4 Growth Inhibition in Human Breast Cancer Cells

In addition to acting as a hematopoietic growth factor, interleukin-4 (IL-4) inhibits growth of some transformed cells in vitro and in vivo. In this study, we show that insulin receptor substrate (IRS)-1, IRS-2, and signal transducer and activator of transcription 6 (STAT6) are phosphorylated follow...

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Bibliografiske detaljer
Main Authors: Gooch, Jennifer L, Christy, Barbara, Yee, Douglas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1531710/
https://ncbi.nlm.nih.gov/pubmed/12082548
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