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Hepatitis Bx Antigen Stimulates Expression of a Novel Cellular Gene, URG4, that Promotes Hepatocellular Growth and Survival

Hepatitis B virus encoded X antigen (HBxAg) may contribute to the development of hepatocellular carcinoma (HCC) by up- or downregulating the expression of cellular genes that promote cell growth and survival. To test this hypothesis, HBxAg-positive and -negative HepG2 cells were constructed, and the...

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Autori principali: Satiroglu Tufan, N Lale, Lian, Zhaorui, Liu, Jie, Pan, Jingbo, Arbuthnot, Patrick, Kew, Michael, Clayton, Marcy M, Zhu, Minghua, Feitelson, Mark A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1531705/
https://ncbi.nlm.nih.gov/pubmed/12082552
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