Cyclin K as a Direct Transcriptional Target of the p53 Tumor Suppressor

Cyclin K, a newly recognized member of the “transcription” cyclin family, may play a dual role by regulating CDK and transcription. Using cDNA microarray technology, we found that cyclin K mRNA was dramatically increased in U373MG, a glioblastoma cell line deficient in wild-type p53, in the presence...

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Main Authors: Mori, Toshiki, Anazawa, Yoshio, Matsui, Kuniko, Fukuda, Seisuke, Nakamura, Yusuke, Arakawa, Hirofumi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2002
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1531701/
https://ncbi.nlm.nih.gov/pubmed/11988847
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