Downregulation and/or Release of NKG2D Ligands as Immune Evasion Strategy of Human Neuroblastoma

Neuroblastoma (NB) is a pediatric extracranial tumor characterized by downregulation of human leukocyte antigen class I and defects of the antigen processing machinery, two features that make it an appropriate target for natural killer (NK)-mediated lysis. NKG2D is an activating immunoreceptor expre...

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Detalhes bibliográficos
Main Authors: Raffaghello, Lizzia, Prigione, Ignazia, Airoldi, Irma, Camoriano, Marta, Levreri, Isabella, Gambini, Claudio, Pende, Daniela, Steinle, Alexander, Ferrone, Soldano, Pistoia, Vito
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1531660/
https://ncbi.nlm.nih.gov/pubmed/15548365
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