The Novel Highly Lipophilic Topoisomerase I Inhibitor DB67 Is Effective in the Treatment of Liver Metastases of Murine CT-26 Colon Carcinoma

Colorectal carcinoma occurs in 1 of 20 individuals in most developed countries. The relapse after resection with metastatic liver disease is a major cause of death. 7-t-Butyldimethylsilyl-10-hydroxycamptothecin (DB67) has been incorporated into liposomes allowing for intravenous (i.v.) administratio...

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Detalhes bibliográficos
Main Authors: Lopez-Barcons, Lluis A, Zhang, Junhong, Siriwitayawan, Gunching, Burke, Thomas G, Perez-Soler, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1531650/
https://ncbi.nlm.nih.gov/pubmed/15548354
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