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A Regulator of G Protein Signaling-containing Kinase Is Important for Chemotaxis and Multicellular Development in Dictyostelium

We have identified a gene encoding RGS domain-containing protein kinase (RCK1), a novel regulator of G protein signaling domain-containing protein kinase. RCK1 mutant strains exhibit strong aggregation and chemotaxis defects. rck1 null cells chemotax ∼50% faster than wild-type cells, suggesting RCK1...

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Main Authors: Sun, Binggang, Firtel, Richard A.
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC153135/
https://ncbi.nlm.nih.gov/pubmed/12686622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-08-0550
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