Extracellular Signal-regulated Kinase Mediates Phosphorylation of Tropomyosin-1 to Promote Cytoskeleton Remodeling in Response to Oxidative Stress: Impact on Membrane Blebbing

Oxidative stress induces in endothelial cells a quick and transient coactivation of both stress-activated protein kinase-2/p38 and extracellular signal-regulated kinase (ERK) mitogen-activated protein kinases. We found that inhibiting the ERK pathway resulted, within 5 min of oxidative stress, in a...

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Autors principals: Houle, François, Rousseau, Simon, Morrice, Nick, Luc, Mario, Mongrain, Sébastien, Turner, Christopher E., Tanaka, Sakae, Moreau, Pierre, Huot, Jacques
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2003
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC153111/
https://ncbi.nlm.nih.gov/pubmed/12686598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-04-0235
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