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A regulatory protein that interferes with activator-stimulated transcription in bacteria

Transcriptional activator proteins in bacteria often operate by interaction with the C-terminal domain of the α-subunit of RNA polymerase (RNAP). Here we report the discovery of an “anti-α” factor Spx in Bacillus subtilis that blocks transcriptional activation by binding to the α-C-terminal domain,...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Nakano, Shunji, Nakano, Michiko M., Zhang, Ying, Leelakriangsak, Montira, Zuber, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153076/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12642660/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0637648100
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