Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells

The surface density of the triggering receptors responsible for the natural killer (NK)-mediated cytotoxicity is crucial for the ability of NK cells to kill susceptible target cells. In this study, we show that transforming growth factor β1 (TGFβ1) down-regulates the surface expression of NKp30 and...

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Hlavní autoři: Castriconi, Roberta, Cantoni, Claudia, Della Chiesa, Mariella, Vitale, Massimo, Marcenaro, Emanuela, Conte, Romana, Biassoni, Roberto, Bottino, Cristina, Moretta, Lorenzo, Moretta, Alessandro
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2003
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC153058/
https://ncbi.nlm.nih.gov/pubmed/12646700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730640100
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