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Visualizing the Ca(2+)-dependent activation of gelsolin by using synchrotron footprinting

Radiolytic protein footprinting with a synchrotron source is used to reveal detailed structural changes that occur in the Ca(2+)-dependent activation of gelsolin. More than 80 discrete peptides segments within the structure, covering 95% of the sequence in the molecule, were examined by footprinting...

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Autors principals: Kiselar, Janna G., Janmey, Paul A., Almo, Steven C., Chance, Mark R.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC153027/
https://ncbi.nlm.nih.gov/pubmed/12655044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0736004100
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