Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10–annexin 2 complex

TRPV5 and TRPV6 constitute the Ca(2+) influx pathway in a variety of epithelial cells. Here, we identified S100A10 as the first auxiliary protein of these epithelial Ca(2+) channels using yeast two-hybrid and GST pull-down assays. This S100 protein forms a heterotetrameric complex with annexin 2 and...

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Bibliografiske detaljer
Main Authors: van de Graaf, Stan F.J., Hoenderop, Joost G.J., Gkika, Dimitra, Lamers, Dennis, Prenen, Jean, Rescher, Ursula, Gerke, Volker, Staub, Olivier, Nilius, Bernd, Bindels, René J.M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC152906/
https://ncbi.nlm.nih.gov/pubmed/12660155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg162
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