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Yeast telomerase is specialized for C/A-rich RNA templates

Telomeres, the protective caps of eukaryotic chromosomes, are maintained by the enzyme telomerase. This telomere-specific reverse transcriptase (RT) uses a small region of its RNA subunit as template to synthesize telomeric DNA, which is generally G/T rich in the strand that contains the 3′ end. To...

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Detalhes bibliográficos
Main Authors: Förstemann, Klaus, Zaug, Arthur J., Cech, Thomas R., Lingner, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152863/
https://ncbi.nlm.nih.gov/pubmed/12626706
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