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A General Population-Genetic Model for the Production by Population Structure of Spurious Genotype–Phenotype Associations in Discrete, Admixed or Spatially Distributed Populations

In linkage disequilibrium mapping of genetic variants causally associated with phenotypes, spurious associations can potentially be generated by any of a variety of types of population structure. However, mathematical theory of the production of spurious associations has largely been restricted to p...

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Hlavní autoři: Rosenberg, Noah A., Nordborg, Magnus
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright © 2006 by the Genetics Society of America 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1526699/
https://ncbi.nlm.nih.gov/pubmed/16582435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.055335
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