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Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages

The 54 kDa subunit of the signal recognition particle (SRP54) binds to the signal sequences of nascent secretory and membrane proteins and it contributes to the targeting of these precursors to the membrane of the endoplasmic reticulum (ER). At the ER membrane, the binding of the signal recognition...

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Autores principales: Römisch, Karin, Miller, Frederick W, Dobberstein, Bernhard, High, Stephen
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1526608/
https://ncbi.nlm.nih.gov/pubmed/16469117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1895
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