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The induction of CCN2 by TGFβ1 involves Ets-1

CCN2 is encoded by an immediate-early gene induced in mesenchymal cells during the formation of blood vessels, bone and connective tissue. It plays key roles in cell adhesion and migration, as well as matrix remodeling. CCN2 is overexpressed in fibrosis, arthritis and cancer; thus, an understanding...

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Bibliografiske detaljer
Main Authors: Van Beek, Jonathan P, Kennedy, Laura, Rockel, Jason S, Bernier, Suzanne M, Leask, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1526589/
https://ncbi.nlm.nih.gov/pubmed/16469114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1890
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