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PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease

We analysed relationships between the PTPN22 1858 polymorphism and antibodies to cyclic citrullinated peptide (CCP), rheumatoid factors (RFs) and the shared epitope (SE) gene (HLA-DRB1*0404 or 0401) and determined their combined predictive value for rheumatoid arthritis (RA) in individuals who subse...

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Detaylı Bibliyografya
Asıl Yazarlar: Johansson, Martin, Ärlestig, Lisbeth, Hallmans, Göran, Rantapää-Dahlqvist, Solbritt
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1526580/
https://ncbi.nlm.nih.gov/pubmed/16507117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1868
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