Mutations at Residues 282, 286, and 293 of Phage λ Integrase Exert Pathway-Specific Effects on Synapsis and Catalysis in Recombination

Bacteriophage λ integrase (Int) catalyzes site-specific recombination between pairs of attachment (att) sites. The att sites contain weak Int-binding sites called core-type sites that are separated by a 7-bp overlap region, where cleavage and strand exchange occur. We have characterized a number of...

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Autors principals: Bankhead, Troy M., Etzel, Bernard J., Wolven, Felise, Bordenave, Sylvain, Boldt, Jeffrey L., Larsen, Teresa A., Segall, Anca M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Enzymes and Proteins
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC152606/
https://ncbi.nlm.nih.gov/pubmed/12670991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.8.2653-2666.2003
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