The CBP Bromodomain and Nucleosome Targeting Are Required for Zta-Directed Nucleosome Acetylation and Transcription Activation

The Epstein-Barr virus (EBV)-encoded lytic activator Zta is a bZIP protein that can stimulate nucleosomal histone acetyltransferase (HAT) activity of the CREB binding protein (CBP) in vitro. We now show that deletion of the CBP bromo- and C/H3 domains eliminates stimulation of nucleosomal HAT activi...

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Autores principales: Deng, Zhong, Chen, Chi-Ju, Chamberlin, Michaela, Lu, Fang, Blobel, Gerd A., Speicher, David, Cirillo, Lisa Ann, Zaret, Kenneth S., Lieberman, Paul M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Transcriptional Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC152567/
https://ncbi.nlm.nih.gov/pubmed/12665567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.8.2633-2644.2003
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