Stability of Colistin and Colistin Methanesulfonate in Aqueous Media and Plasma as Determined by High-Performance Liquid Chromatography

The stabilities of colistin and colistin methanesulfonate (CMS) in different aqueous media were studied by specific high-performance liquid chromatography (HPLC) methods. Colistin was stable in water at 4 and 37°C for up to 60 days and 120 h, respectively. However, degradation was observed when coli...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Li, Jian, Milne, Robert W., Nation, Roger L., Turnidge, John D., Coulthard, Kingsley
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152538/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654671/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.4.1364-1370.2003
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