Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population

BACKGROUND: The protein tyrosine phosphatase-1B, a negative regulator for insulin and leptin signalling, potentially modulates glucose and energy homeostasis. PTP1B is encoded by the PTPN1 gene located on chromosome 20q13 showing linkage with type 2 diabetes (T2D) in several populations. PTPN1 gene...

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Main Authors: Cheyssac, Claire, Lecoeur, Cécile, Dechaume, Aurélie, Bibi, Amina, Charpentier, Guillaume, Balkau, Beverley, Marre, Michel, Froguel, Philippe, Gibson, Fernando, Vaxillaire, Martine
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2006
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1525165/
https://ncbi.nlm.nih.gov/pubmed/16677372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-7-44
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