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HoxB domain induction silences DNA replication origins in the locus and specifies a single origin at its boundary

In multicellular organisms, changes in the DNA replication programme could act to integrate differentiation with cell division in various developmental and transcriptional contexts. Here, we have addressed the use of DNA replication origins during differentiation in the HoxB domain—a cluster of nine...

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Detalhes bibliográficos
Main Authors: Grégoire, Damien, Brodolin, Konstantin, Méchali, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1525151/
https://ncbi.nlm.nih.gov/pubmed/16845368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400758
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