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Direct comparison of nick-joining activity of the nucleic acid ligases from bacteriophage T4

The genome of bacteriophage T4 encodes three polynucleotide ligases, which seal the backbone of nucleic acids during infection of host bacteria. The T4Dnl (T4 DNA ligase) and two RNA ligases [T4Rnl1 (T4 RNA ligase 1) and T4Rnl2] join a diverse array of substrates, including nicks that are present in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bullard, Desmond R., Bowater, Richard P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1525015/
https://ncbi.nlm.nih.gov/pubmed/16671895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060313
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