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Mutational analysis of the intramembranous H10 loop of yeast Nhx1 reveals a critical role in ion homoeostasis and vesicle trafficking

Yeast Nhx1 [Na(+)(K(+))/H(+) exchanger 1] is an intracellular Na(+)(K(+))/H(+) exchanger, localizing to the late endosome where it is important for ion homoeostasis and vesicle trafficking. Phylogenetic analysis of NHE (Na(+)/H(+) exchanger) sequences has ident-ified orthologous proteins, including...

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Detalhes bibliográficos
Main Authors: Mukherjee, Sanchita, Kallay, Laura, Brett, Christopher L., Rao, Rajini
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1525006/
https://ncbi.nlm.nih.gov/pubmed/16671892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060388
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