Pharmacokinetics and Efficacy of Linezolid in a Gerbil Model of Streptococcus pneumoniae-Induced Acute Otitis Media

The oxazolidinone linezolid represents a new antibacterial class of potential benefit in managing multidrug-resistant gram-positive infections, including those caused by Streptococcus pneumoniae. In a gerbil model of acute otitis media (AOM) induced by either penicillin-resistant S. pneumoniae (PRSP...

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Detalhes bibliográficos
Main Authors: Humphrey, William R., Shattuck, Mark H., Zielinski, Raymond J., Kuo, Ming-Shang T., Biermacher, John J., Smith, Donald P., Jensen, Jana L., Schaadt, Ronda D., Zurenko, Gary E., Richards, Ivan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152499/
https://ncbi.nlm.nih.gov/pubmed/12654670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.4.1355-1363.2003
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