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The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications
Epidermal growth factor receptor (EGFR) is a member of the ErbB family of receptors. Its stimulation by endogenous ligands, EGF or transforming growth factor-alpha (TGF-α) results in activation of intracellular tyrosine kinase, therefore, cell cycle progression. High levels of EGFR expression are co...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1524965/ https://ncbi.nlm.nih.gov/pubmed/16722544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-1-11 |
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