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Conventional 3′ end formation is not required for NMD substrate recognition in Saccharomyces cerevisiae
The recognition and rapid degradation of mRNAs with premature translation termination codons by the nonsense-mediated pathway of mRNA decay is an important RNA quality control system in eukaryotes. In mammals, the efficient recognition of these mRNAs is dependent upon exon junction complex proteins...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2006
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1524890/ https://ncbi.nlm.nih.gov/pubmed/16809819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.92706 |
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