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Heterozygous carriers of Nijmegen Breakage Syndrome have a distinct gene expression phenotype

Autosomal recessive diseases are those that require mutations in both alleles to exhibit the disorder. Although most recessive conditions are rare, heterozygous carriers of recessive mutations are quite common. In this study, we show that carriers of Nijmegen Breakage Syndrome (NBS) have a distinct...

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Autors principals: Cheung, Vivian G., Ewens, Warren J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1524869/
https://ncbi.nlm.nih.gov/pubmed/16809669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5320706
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