Diesel exhaust particles increase IL-1β-induced human β-defensin expression via NF-κB-mediated pathway in human lung epithelial cells

BACKGROUND: Human β-defensin (hBD)-2, antimicrobial peptide primarily induced in epithelial cells, is a key factor in the innate immune response of the respiratory tract. Several studies showed increased defensin levels in both inflammatory lung diseases, such as cystic fibrosis, diffuse panbronchio...

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Main Authors: Nam, Hae Yun, Ahn, Eun-Kyung, Kim, Hyung Jung, Lim, Young, Lee, Chun Beoun, Lee, Kyo Young, Vallyathan, Val
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1524805/
https://ncbi.nlm.nih.gov/pubmed/16723032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-3-9
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