Substrate Specificity and Enantioselectivity of 4-Hydroxyacetophenone Monooxygenase

The 4-hydroxyacetophenone monooxygenase (HAPMO) from Pseudomonas fluorescens ACB catalyzes NADPH- and oxygen-dependent Baeyer-Villiger oxidation of 4-hydroxyacetophenone to the corresponding acetate ester. Using the purified enzyme from recombinant Escherichia coli, we found that a broad range of ca...

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Detalhes bibliográficos
Main Authors: Kamerbeek, Nanne M., Olsthoorn, Arjen J. J., Fraaije, Marco W., Janssen, Dick B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Enzymology and Protein Engineering
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152415/
https://ncbi.nlm.nih.gov/pubmed/12514023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.1.419-426.2003
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