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E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex

Despite biochemical and genetic data suggesting that E2F and pRB (pocket protein) families regulate transcription via chromatin-modifying factors, the precise mechanisms underlying gene regulation by these protein families have not yet been defined in a physiological setting. In this study, we have...

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Publicat a:Genes Dev
Autors principals: Rayman, Joseph B., Takahashi, Yasuhiko, Indjeian, Vahan B., Dannenberg, Jan-Hermen, Catchpole, Steven, Watson, Roger J., te Riele, Hein, Dynlacht, Brian David
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152357/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959842/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.969202
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